Cambridge genome aces help identify new breast cancer threats

Cambridge genome aces help identify new breast cancer threats

The optimal amount of physical activity is hard to define, but I would suggest at least doing 30 minutes of exercise five days a week to decrease the risk of breast cancer development in the general population.

In addition a further 10 genetic variants specifically linked to stubborn breast cancers that do not respond to hormone treatment were found. "There are some clear patterns in the genetic variants that should help us understand why some women are predisposed to breast cancer, and which genes and mechanisms are involved". "It is estimated that worldwide over 508 000 women died in 2011 due to breast cancer", WHO. Seven of the mutations found lead to a type of breast cancer that doesn't respond to traditional hormonal therapies, like tamoxifen.

"As well as identifying new genetic variants, we have also confirmed many that we had previously suspected".

Yet breast cancer is still one of the most deadly forms of cancer for many women in the U.S., coming second only to lung cancer for some demographic groups. "Our Making Strides Against Breast Cancer walk ensures no one faces breast cancer alone by bringing the community together, funding innovative breast cancer research, promoting education and risk reduction, and providing comprehensive patient support to those who need it most".

'This should provide guidance for a lot of future research, ' he added.

Others, known as oestrogen-receptor negative, are not affected by the hormone and are more hard to treat.

By analysing the 180 regions of the genome where are located some of the variations that predispose to breast cancer, it will be possible to determine the risk of a woman developing this cancer.

More news: Men Gave Nazi Salutes And Shot At Protesters After Richard Spencer's Speech

Among breast cancer sufferers, those who rely on herbs, homeopathy or energy crystals to beat their disease are 5.68 times more at risk of an early death, a study found.

Read the full ER-negative study in Nature Genetics.

The additions almost double the number of genetic markers known to scientists, providing a trove of data for future studies to investigate in search of better understanding, new detection methods, and potentially more effective treatments.

"If you could stop that (cancer) from ever happening to you that would change my quality of life and it would have meant I could have had a second child".

"Some of the variations are protective, others increase the risk".

"Many women are offered mammogram screening when they are middle-aged, but if we know a woman has genetic markers that place her at higher risk of breast cancer, we can recommend more intensive screening at a younger age", says Chenevix-Trench.

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